Pbx acts with Hand2 in early myocardial differentiation
نویسندگان
چکیده
منابع مشابه
Hand2 Regulates Epithelial Formation during Myocardial Differentiation
Myocardial differentiation is initiated by the activation of terminal-differentiation gene expression within a subset of cells in the anterior lateral plate mesoderm. We have previously shown that shortly after this activation, myocardial cells undergo epithelial maturation [1], suggesting that myocardial differentiation encompasses both molecular and cellular changes. To address the question o...
متن کاملHEART RATE: A PREDICTOR OF EARLY MORTALITY IN PATIENTS WITH MYOCARDIAL INFARCTION
A number of epidemiologic studies have reported a positive relationship between heart rate, cardiovascular disease and mortality. To examine the correlation between heart rate and mortality after acute myocardial infarction (AMI), 2147 patients hospitalized in coronary care units in Isfahan were investigated in a cross-sectional study. Their heart rate was measured according to an electroca...
متن کاملDrosophila Heartless Acts with Heartbroken/Dof in Muscle Founder Differentiation
The formation of a multi-nucleate myofibre is directed, in Drosophila, by a founder cell. In the embryo, founders are selected by Notch-mediated lateral inhibition, while during adult myogenesis this mechanism of selection does not appear to operate. We show, in the muscles of the adult abdomen, that the Fibroblast growth factor pathway mediates founder cell choice in a novel manner. We suggest...
متن کاملHand2 controls osteoblast differentiation in the branchial arch by inhibiting DNA binding of Runx2.
Members of the basic helix-loop-helix (bHLH) family of transcription factors regulate the specification and differentiation of numerous cell types during embryonic development. Hand1 and Hand2 are expressed by a subset of neural crest cells in the anterior branchial arches and are involved in craniofacial development. However, the precise mechanisms by which Hand proteins mediate biological act...
متن کاملTGF-β1 enhanced myocardial differentiation through inhibition of the Wnt/β-catenin pathway with rat BMSCs
Objective(s): To investigate and test the hypotheses that TGF-β1 enhanced myocardial differentiation through Wnt/β-catenin pathway with rat bone marrow mesenchymal stem cells (BMSCs).Materials and Methods: Lentiviral vectors carrying the TGF-β1 gene were transduced into rat BMSCs firstly. Then several kinds of experimental methods were u...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Developmental Biology
سال: 2009
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2009.07.004